At CSAN - CNR I carried out my work for research programs of the CNR (as P.I.), of the University "La Sapienza", of the MURST and of the Pasteur Institute-Cenci Bolognetti Foundation, aimed at studying the relationships between structure and functions chromatin by chemical, biochemical, biological molecular and microscopy (TEM and AFM) methods. At the Rome Section of the ICRM, now SCITEC, located at the Institute of Biochemistry and Clinical Biochemistry, of the Catholic University of the Sacred Heart, I deal with: 1- Expression of genes implicated in apoptotic phenomena and oxidative stress in cell cultures and rat or mouse tissue by molecular biology methods; 2- Analysis of telomerase activity by TRAP assay in immortalized cells in the presence of compounds with alleged anti-tumor activity; 3- Analysis by visualization with AFM of the aging of the red blood cell; 4- Analysis of mitochondrial DNA damage.
Degree in Biological Sciences in 1983 at the University of Rome "Sapienza";
Professional training allowance at the "Study Center for Nucleic Acids" (CSAN) of CNR from 1982 to 1990;
In 1985, qualification to practice the profession of Biologist. Registration on the Special List of the National Order of Biologists;
Technician (CTER) at the “Study Center for Nucleic Acids” (CSAN) of CNR from 1990 to 2002.
From 2002 to 2007 CTER at the IRCM of the CNR (Rome Section);
Since 2007 III level Technologist at the same Institute.
Collaborator for CNR-NRC Joint project (Egypt) “Design, synthesis and biological evaluation of new chalcone-based-fibrates as PPAR-a agonists, with Dr Francesca Sciandra as Italian P.I:, (2018-2020). Collaborator for THE NANDO AND ELSA PERETTI FOUNDATION “Individuation of the S100B protein as a therapeutic target in multiple sclerosis pathogenic processes” Prof. Fabrizio Michetti as P.I.
ASI Project “Countermeasures Against space Radiation and Microgravity induced brain lesions (CARM)” with Prof. Sergio Capaccioli as P.I. collaborator to Dr Stefano Cacchione as head of U.R..(2011-2014)
Structural biology, gene expression, molecular biology, microscopy
Protein and Nucleic Acid extraction, Protein / Nucleic acid bond analysis, Real-timeP CR, TEM and AFM microscopy, Telomerase activity analysis, Mitochondrial DNA damage analysis.