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Cristina D’Arrigo

Lead Researcher

RESEARCH ACTIVITY

Scaffold’s preparation based on functionalized alginate for tissutal rigeneration. Using electron microscopical techniques (SEM) is analyzed the hydrogel morphology and porosity, with thermogravimetric characterization and analysis by FTIR their decomposition is followed and with other methodologies the mechanical and swelling properties are determined, to  relate the above-mentioned properties to the results of different types of cellular seedings. I’ve also dealed in the morphological studies (SEM, TEM) of tissues from oncological biopsies and of cellular organels  involved in Hodgkin lymphoma spreading, with relative image analysis by ImageJ software. Since 2018 I have dealt with spectroscopic and morphological studies of proteins involved in neurodegenerative diseases as Alzheimer. I partecipate in dissemination activity of research in different events (Science Festival, school seminars etc.).

PROJECTS

- ‘Sulfur-based Polymers from Inverse Vulcanization as high refractive index materials for all-polymer planar phOTonic crystals’ - PIVOT (ID ROL 20583), Fondazione Compagnia di San Paolo, Coord. P. Stagnaro-partecipant- 2018-2020.
- ‘Developing and Implementing Sustainability-Based Solutions for Bio-Based Plastic Production and Use to Preserve Land and Sea Environmental Quality in Europe’ – BIO-PLASTICS EUROPE (nr. 860407), H2020-CP-IA-2017, Coord. W. Leal HAW Hamburg, Resp. RU SCITEC-CNR P. Stagnaro-partecipant- 2019-2023.

-“From bio-inspired molecules to Alzheimer’s Disease prevention”-BIMAP-Dr Cristina D’Arrigo-coordinator-2016-2018
- “Structural insights on oligomers of Aβ peptides in the presence of PrP”-NIRG-Dott.ssa Simona Tomaselli-UR responsible-2014-2016
- “ADAM10 as therapeutic target to enhance the anti-tumor response in Hodgkin lymphoma: development of specific inhibitors”-Dr Maria Raffaella Zocchi-partecipant-2015-2018
- “States and Kinetics of Oligomerization and Fibrillization of Beta-amyloids in Alzheimer Disease”- BASKO-Dr Cristina D’Arrigo-coordinator-2009-2012

RESEARCH INTERESTS

Hydrogels, alginate, biopolymers, morphology, aggregation kinetics and conformation’s changes.

SCIENTIFIC SKILLS

SEM and TEM Microscopy, image analysis, UV spectroscopy, circular dichroism dicroism and fluorescence spectroscopy.

RESEARCH AREA

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Research Groups

GEMMALab

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