Maria Cristina De Rosa

Since 1997 MCDR leads the molecular modelling and drug discovery unit at SCITEC Secondary Section of Rome. Her scientific activity focuses on computational simulations aimed to study structure, function and properties of biological systems involved in pathological diseases and characterize ligand-protein and protein-protein molecular recognition for drug design strategies. The computational chemistry facility at SCITEC-Rome consists of a cluster of workstations equipped with the most performant and advanced commercial and academic software for protein modelling, molecular dynamics simulations, virtual screening, rational drug design. Among the most important findings of her research activity the patenting of few small molecules able to selectively block the immune response to the self antigen in rheumatoid arthritis and the patenting of novel kinase inhibitors which displayed activity against solid tumours.

2018 National Scientific Habilitation as Full Professor in Biochemistry
From 2017 Chief of ICRM (SCITEC), Rome, CNR
From 1997 Researcher of ICRM, Rome, CNR
1996 Visiting scientist Laboratory of Molecular Biophysics Univ. Oxford-UK
1994-95 Collaboration contract with Pharmacia-Upjohn
1993-94 Visiting scientist Dep. of Biotechnology, Chemistry and Pharmacy Univ. Siena
1990-93 CNR three-year Postgraduate Research Fellowship
1989-90 Collaboration contract with Tecnofarmaci
1989 Habilitation to the Profession of Chemist, Sapienza Univ. Rome
1988 Degree in Chemistry (110/110 with honors), Sapienza, Univ. Rome