Benedetta Righino's research activity focuses mainly on the study of the structure-function relationships of proteins through in silico methodologies and on the identification and design of biologically active compounds against macromolecular targets of pharmaceutical interest using computational techniques. In particular, his research experience included theoretical folding studies, analysis of the effects of mutations on biological macromolecules, protein-ligand and protein-protein interaction studies through molecular modeling techniques and molecular dynamics simulations. She also worked in drug discovery projects aimed at identifying biologically active small molecules using docking techniques and ligand-structure-pharmacophore-based virtual screening. She is among the inventors of two patents on new kinase inhibitors active against solid tumors.
B.R. achieved her master degree in Pharmaceutical Chemistry from the "University of Rome-Sapienza" in 2014 and received the PhD from the Catholic University of the Sacred Heart (UCSC)-Rome in "Sciences of Nutrition, metabolism, aging and gender pathologies (Molecular Medicine)” in 2018 also carrying out an Internship in the "Computational Chemistry Lab” of Prof. Langer in Vienna. She has carried out research in computational chemistry at the UCSC and is adjunct professor of Pharmaceutical Chemistry in the course of Cosmetic Sciences and Technologies (Faculty of Medicine and Surgery-UCSC Rome).
Computational chemistry, protein modeling, in silico design of bioactive molecules, structural biology.
Molecular Modeling, Virtual Screening, Drug Discovery, Computational Structural Biology