Synthesis and modification of bioactive compounds


SCITEC – which is a key contact point for chemical and biochemical research – collaborates with a number of life-sciences stakeholders (IRCCS, hospitals e translational medicine departments, companies) on topics spanning the design of new molecules, their synthesis and relative structural modifications, as well as their bioconjugation to a wide range of scaffolds including nanoparticles, proteins and antibodies, with the aim of identifying tools for biomedical research, such as experimental diagnostics and therapeutics, bioactive peptides, fluorophores and tracers for biomedical imaging, recombinant proteins. These tools are then validated in vitro and ex-vivo with the view of subsequently studying their biological/pharmacological activity in vivo.
The final goal is the identification of novel small molecule drug candidates, diagnostics for biomedical imaging, and molecular tools for interrogating biological systems.


  • Organic synthesis and catalysis
  • Medicinal chemistry and SAR studies
  • Organofluorine chemistry
  • Enzymatic synthesis and biocatalysis
  • Solid-phase peptide synthesis
  • Bioorthogonal and “click” chemistry
  • Analytical and spectroscopic characterisation of organic molecules
We use cookies

We use cookies on our website. Some of them are essential for the operation of the site, while others help us to improve this site and the user experience (tracking cookies). You can decide for yourself whether you want to allow cookies or not. Please note that if you reject them, you may not be able to use all the functionalities of the site.