Her research interests focus on the synthesis of peptidomimetics and other bioactive molecules as modulators of protein-protein interactions, with a wide experience in the field of integrin ligands synthesis and conjugation. She has also developed competences in performing in vitro binding assays on isolated receptors.
She has recently added the interest in nanomedicine and in particular in the synthesis and functionalization of nanoparticles to be employed as tools to study biological interactions or as drug delivery systems.
PROJECTS
PRIN2015 “Tumor-targeting peptidomimetics: synthesis and bio-medical applications” - Prof. C. Gennari (University of Milan) – partecipant – 2017-2020.
H2020 ITN Networks “MagicBullet Reloaded” – Prof. N. Sewald (Bielefeld University) – partecipant – 2019-2023.
FIRB - FUTURO IN RICERCA “Utilizzo di approcci computazionali per la progettazione di peptidomimetici diretti verso la N-caderina, loro sintesi e valutazione biologica come agenti antitumorali.” – Dr. M. Civera (University of Milan) – partecipant – 2010-2014
PRIN2010-2011 “Synthesis and biomedical applications of tumor-targeting peptidomimetics” - Prof. C. Gennari (University of Milan)– partecipant – 2013-2016.
CNR-Regione Lombardia “Ricerca e sviluppo di prodotti e piattaforme tecnologiche per la competitività dell’industria lombarda” – RSPPTech – Dott. A. Ponti (CNR-ISTM)– partecipant - 2013-2015
H2020 ITN Networks “MagicBullet” – Prof. N. Sewald (Bielefeld University) – partecipant – 2015-2018
RESEARCH INTERESTS
Organic chemistry; peptidomimetics; protein-protein interactions; integrins; nanoparticles functionalization
SCIENTIFIC SKILLS
Organic synthesis; conjugation of bio-molecules, synthesis and functionalization of nanoparticles, binding assays on isolated receptors
RESEARCH AREA
