CHEMISTRY AND ENERGY

Abstract: 3D-FARE is aimed to demonstrate a proof of principle for a novel platform for the highly sensitive detection biomarkers. The system merges complementary expertise where ultrabright Ir luminophores are associated to the 3D-FARE electrodes containing open porous structures and concur to the generation of intense electrogenerated chemiluminescence (ECL). ECL is produced.according to the coreactant approach where an excited state is generated through the reaction between the fluorophore and the co-reactant, both oxidised at the electrode. Scientifically, the proposed strategyrests on three pillars:
(i) tailored design of 3D mesoporous electrodes suited for the interaction with cells and biomolecules and their fabrication according to either top-down or bottom-up strategies;
(ii) development of novel ultrabright Ir organometallic luminophores suited for the bioconjugation;
(iii) assembly of an analytical platform for highly sensitive ECL imaging of cells 

Activity : 2018-2022