Integrated nanoparticle isolation and detection system for complete on-chip analysis of exosomes - INDEX
Abstract: The aim of Project INDEX is to isolate and characterize nanoparticles available in bodily fluids through the development and integration of novel technological breakthroughs. The technology will enable the analysis of clinically valuable nanoparticles called exosomes towards new generation diagnostics. Exosomes are known to mediate communication between cells and their effective utilization holds a great promise of revolutionizing the standard of clinical care. However, their detection and molecular profiling are technically challenging. The proposed technology will isolate exosomes that are as small as 30nm in diameter from human plasma with high purity, and provide an in-depth, multi-parameter characterization of the particles through digital counting, size determination, and biological phenotyping.
Activity : 2017-2021